Robert G. Louis Jr, MD

Dr. Robert Louis, MD, is a highly trained and fellowship-certified brain and spine surgeon in Orange County, specializing in minimally invasive neurosurgical techniques. Raised in a Boston suburb, he completed his undergraduate studies at Boston University before earning his medical degree. He then pursued a prestigious neurosurgical residency at the University of Virginia under Dr. John Jane, completing over 1,200 cases across cranial and spinal neurosurgery. His training emphasized complex brain tumor, skull base, and pituitary surgery, including extensive mentorship under Dr. Edward Oldfield, a world-renowned pituitary surgeon. To further refine his expertise, Dr. Louis completed a fellowship in Minimally Invasive Neurosurgery at the John Wayne Cancer Institute under Dr. Daniel Kelly, making him the only fellowship-trained minimally invasive neurosurgeon in Orange County. 

As the Director of the Skull Base and Pituitary Tumor Program at Hoag Memorial Hospital, Dr. Louis specializes in endoscopic and minimally invasive procedures for brain, skull base, and sellar tumors. Utilizing advanced neuroimaging and navigation, he employs keyhole neurosurgery to minimize disruption to surrounding structures, reducing post-operative pain and complications while promoting faster recovery. His expertise also extends to a range of minimally invasive spine procedures, including anterior cervical discectomy and fusion, artificial cervical disc arthroplasty, and posterior cervical fusion with instrumentation. Dedicated to innovation, he continuously integrates the latest advancements in neurosurgical techniques to improve patient outcomes. 

Beyond his clinical practice, Dr. Louis is deeply involved in research, with a particular interest in microsurgical neuroanatomy and the development of novel neurosurgical procedures. He has authored over 60 peer-reviewed scientific publications and contributed to numerous book chapters, furthering the field’s understanding of neuroanatomy and surgical advancements. His commitment to both patient care and research ensures that he remains at the forefront of neurosurgery, offering cutting-edge treatments that enhance both safety and efficacy.